POLR3C 抗体 (Internal Region)
Quick Overview for POLR3C 抗体 (Internal Region) (ABIN6259155)
抗原
See all POLR3C 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- RPC3 Antibody detects endogenous levels of total RPC3.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human RPC3, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) antibody
POLR3C 适用: 人 WB, IF, IHC (p), IHC 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) antibodyPOLR3C 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) antibodyPOLR3C 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) antibodyPOLR3C 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) antibodyPOLR3C 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (C-Term) antibodyPOLR3C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-270) antibodyPOLR3C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 202-230) antibodyPOLR3C 适用: 人 WB 宿主: 兔 Polyclonal RB36947 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (Middle Region) antibodyPOLR3C 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- POLR3C (Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))
-
别名
- POLR3C
-
背景
-
Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. Preferentially binds single-stranded DNA (ssDNA) in a sequence-independent manner (PubMed:21358628).
Gene: POLR3C
-
分子量
- 60 kDa
-
基因ID
- 10623
-
UniProt
- Q9BUI4
抗原
-
