nectin-3 抗体 (Internal Region)
Quick Overview for nectin-3 抗体 (Internal Region) (ABIN6259135)
抗原
See all nectin-3 (NECTIN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- PVRL3 Antibody detects endogenous levels of total PVRL3.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PVRL3, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 282-404) antibody
NECTIN3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6D5B2 unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 84-97), (Extracellular) antibodyNECTIN3 适用: 小鼠 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 59-166) antibodyNECTIN3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 90-293) antibodyNECTIN3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 310-549) antibodyNECTIN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) antibodyNECTIN3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 171-377) antibodyNECTIN3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (Center) antibodyNECTIN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) antibodyNECTIN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (Internal Region) antibodyNECTIN3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
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别名
- NECTIN3
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背景
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Description: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Gene: NECTIN3
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分子量
- 61 kDa
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基因ID
- 25945
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UniProt
- Q9NQS3
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途径
- Cell-Cell Junction Organization
抗原
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