EPH Receptor B4 抗体 (C-Term)
Quick Overview for EPH Receptor B4 抗体 (C-Term) (ABIN6259079)
抗原
See all EPH Receptor B4 (EPHB4) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- EPHB4 Antibody detects endogenous levels of total EPHB4.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human EPHB4, corresponding to a region within C-terminal amino acids.
-
亚型
- IgG
-
-
anti-EPH Receptor B4 (EPHB4) (AA 472-486), (Extracellular) antibody
EPHB4 适用: 小鼠 WB, IHC, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B4 (EPHB4) (AA 300-540) antibodyEPHB4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B4 (EPHB4) antibodyEPHB4 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 5B8F7 unconjugated
anti-EPH Receptor B4 (EPHB4) antibodyEPHB4 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 5B5 unconjugated
anti-EPH Receptor B4 (EPHB4) (AA 198-323) antibodyEPHB4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-EPH Receptor B4 (EPHB4) (AA 562-612) antibodyEPHB4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7H4A6 unconjugated
anti-EPH Receptor B4 (EPHB4) antibodyEPHB4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14731 unconjugated
anti-EPH Receptor B4 (EPHB4) (Internal Region) antibodyEPHB4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B4 (EPHB4) (AA 889-923), (C-Term) antibodyEPHB4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50408 unconjugated
anti-EPH Receptor B4 (EPHB4) (Internal Region) antibodyEPHB4 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- EPH Receptor B4 (EPHB4)
-
别名
- EPHB4
-
背景
-
Description: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
Gene: EPHB4
-
分子量
- 108 kDa
-
基因ID
- 2050
-
UniProt
- P54760
-
途径
- RTK signaling
抗原
-
