MSH3 抗体 (N-Term)
Quick Overview for MSH3 抗体 (N-Term) (ABIN6259074)
抗原
See all MSH3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- MSH3 Antibody detects endogenous levels of total MSH3.
-
预测反应
- Pig,Horse,Sheep,Dog
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human MSH3, corresponding to a region within N-terminal amino acids.
-
亚型
- IgG
-
-
anti-MutS Homolog 3 (MSH3) (N-Term) antibody
MSH3 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 651-750) antibodyMSH3 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 521-620) antibodyMSH3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 51-100) antibodyMSH3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 617-761) antibodyMSH3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- MSH3 (MutS Homolog 3 (MSH3))
-
别名
- MSH3
-
背景
-
Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Gene: MSH3
-
分子量
- 127 kDa
-
基因ID
- 4437
-
UniProt
- P20585
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-
