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PARP2 抗体 (Internal Region)

This 兔 多克隆 anti-PARP2 antibody specifically detects PARP2 in WB, ELISA, IF 和 ICC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6259061
发货至: 中国
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中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PARP2 抗体 (Internal Region) (ABIN6259061)

抗原

See all PARP2 抗体
PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

适用

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人, 小鼠

宿主

  • 65
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  • 1

克隆类型

  • 46
  • 24
多克隆

标记

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This PARP2 antibody is un-conjugated

应用范围

  • 47
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    Internal Region

    特异性

    PARP2 Antibody detects endogenous levels of total PARP2.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PARP2, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

    别名

    PARP2

    背景

    Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768). This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231). Mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity (PubMed:28190768).

    Gene: PARP2

    分子量

    75 kDa

    基因ID

    10038

    UniProt

    Q9UGN5

    途径

    DNA Damage Repair
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