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FZD10 抗体

This anti-FZD10 antibody is a 兔 多克隆 antibody detecting FZD10 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 猴.
产品编号 ABIN6258746
发货至: 中国
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Quick Overview for FZD10 抗体 (ABIN6258746)

抗原

See all FZD10 抗体
FZD10 (Frizzled Family Receptor 10 (FZD10))

适用

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人, 小鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This FZD10 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 特异性

    FZD10 antibody detects endogenous levels of total FZD10

    交叉反应

    人, 猴, 小鼠

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    FZD10 (Frizzled Family Receptor 10 (FZD10))

    别名

    FZD10

    背景

    Description: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).

    Gene: FZD10

    分子量

    65 kDa

    基因ID

    11211

    UniProt

    Q9ULW2

    途径

    WNT signaling
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