NEIL3 抗体 (C-Term)
Quick Overview for NEIL3 抗体 (C-Term) (ABIN6258631)
抗原
See all NEIL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- NEIL3 Antibody detects endogenous levels of total NEIL3.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NEIL3, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 2-187) antibody
NEIL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) antibodyNEIL3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 292-320) antibodyNEIL3 适用: 人 WB 宿主: 兔 Polyclonal RB40413 unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) antibodyNEIL3 适用: 人 DB 宿主: 小鼠 Monoclonal 2627C1b unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
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别名
- NEIL3
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背景
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Description: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA, also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.
Gene: NEIL3
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分子量
- 68 kDa
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基因ID
- 55247
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UniProt
- Q8TAT5
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途径
- DNA Damage Repair
抗原
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