ATG16L1 抗体 (C-Term)
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北京 101111
Quick Overview for ATG16L1 抗体 (C-Term) (ABIN6258588)
抗原
See all ATG16L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- ATG16L1 Antibody detects endogenous levels of total ATG16L1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ATG16L1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 200-300) antibody
ATG16L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 342-607) antibodyATG16L1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 1-284) antibodyATG16L1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 11-257) antibodyATG16L1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5H9A11 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 161-190) antibodyATG16L1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB07490 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 84-114) antibodyATG16L1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 501-607) antibodyATG16L1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 90-300) antibodyATG16L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 11-257) antibodyATG16L1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8F8C2 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 90-300) antibodyATG16L1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
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别名
- ATG16L1
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背景
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Description: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966).
Gene: ATG16L1
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分子量
- 69 kDa
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基因ID
- 55054
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UniProt
- Q676U5
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途径
- Autophagy
抗原
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