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TCHP 抗体 (C-Term)

This 兔 多克隆 anti-TCHP antibody specifically detects TCHP in ELISA, WB, IHC, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN6258431
发货至: 中国
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Quick Overview for TCHP 抗体 (C-Term) (ABIN6258431)

抗原

See all TCHP 抗体
TCHP (Trichoplein, Keratin Filament Binding (TCHP))

适用

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宿主

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克隆类型

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多克隆

标记

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This TCHP antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    C-Term

    特异性

    TCHP Antibody detects endogenous levels of total TCHP.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TCHP, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    TCHP (Trichoplein, Keratin Filament Binding (TCHP))

    别名

    TCHP

    背景

    Description: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).

    Gene: TCHP

    分子量

    ?65 kDa

    基因ID

    84260

    UniProt

    Q9BT92
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