TCHP 抗体 (C-Term)
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北京 101111
Quick Overview for TCHP 抗体 (C-Term) (ABIN2788476)
抗原
See all TCHP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- TCHP Antibody - C-terminal region
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序列
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
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预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 91%
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产品特性
- This is a rabbit polyclonal antibody against TCHP. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TCHP
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anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 291-320) antibody
TCHP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24714 unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 1-498) antibodyTCHP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 387-436) antibodyTCHP 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (C-Term) antibodyTCHP 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (C-Term) antibodyTCHP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Trichoplein, Keratin Filament Binding (TCHP) (AA 306-370), (Middle Region) antibodyTCHP 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60515-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation." in: PLoS ONE, Vol. 11, Issue 1, pp. e0143235, (2016) (PubMed).
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- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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别名
- TCHP
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背景
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Background Information: TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
Gene Name: Trichoplein, keratin filament binding
Alternative Symbols: TpMs
Protein Name: Trichoplein keratin filament-binding protein
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分子量
- 61kDa
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基因ID
- 84260
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NCBI登录号
- NP_115676
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UniProt
- Q9BT92
抗原
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