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UBE2D2 抗体 (C-Term)

This anti-UBE2D2 antibody is a 兔 多克隆 antibody detecting UBE2D2 in WB, ELISA, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6258351
发货至: 中国

Quick Overview for UBE2D2 抗体 (C-Term) (ABIN6258351)

抗原

See all UBE2D2 抗体
UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This UBE2D2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    特异性

    UBE2D2 Antibody detects endogenous levels of total UBE2D2.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human UBE2D2, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

    别名

    UBE2D2

    背景

    Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

    Gene: UBE2D2

    分子量

    17 kDa

    基因ID

    7322

    UniProt

    P62837

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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