ULK3 抗体 (Internal Region)
Quick Overview for ULK3 抗体 (Internal Region) (ABIN6258344)
抗原
See all ULK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ULK3 Antibody detects endogenous levels of total ULK3.
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预测反应
- Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ULK3, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Unc-51-Like Kinase 3 (ULK3) (AA 435-468), (C-Term) antibody
ULK3 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 1404CT148-89-25 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 427-454), (C-Term) antibodyULK3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 14-43), (N-Term) antibodyULK3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12633 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 44-240) antibodyULK3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 1-214) antibodyULK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 445-458) antibodyVerified ULK3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (C-Term) antibodyVerified ULK3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 324-373) antibodyULK3 适用: 人, 小鼠, 大鼠, 犬, Pig, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ULK3 (Unc-51-Like Kinase 3 (ULK3))
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别名
- ULK3
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背景
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Description: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
Gene: ULK3
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分子量
- 24 kDa
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基因ID
- 25989
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UniProt
- Q6PHR2
抗原
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