SMO 抗体 (N-Term)
Quick Overview for SMO 抗体 (N-Term) (ABIN6258327)
抗原
See all SMO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- SMO Antibody detects endogenous levels of total SMO.
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预测反应
- Pig,Bovine,Horse,Rabbit,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SMO, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SMO (Smoothened Homolog (Drosophila) (SMO))
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别名
- SMO
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背景
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Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed:19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation (By similarity).
Gene: SMO
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分子量
- 86 kDa
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基因ID
- 6608
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UniProt
- Q99835
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途径
- Hedgehog Signaling
抗原
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