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SMO 抗体 (N-Term)

This anti-SMO antibody is a 兔 多克隆 antibody detecting SMO in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6258327
发货至: 中国

Quick Overview for SMO 抗体 (N-Term) (ABIN6258327)

抗原

See all SMO 抗体
SMO (Smoothened Homolog (Drosophila) (SMO))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SMO antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    特异性

    SMO Antibody detects endogenous levels of total SMO.

    预测反应

    Pig,Bovine,Horse,Rabbit,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human SMO, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    SMO (Smoothened Homolog (Drosophila) (SMO))

    别名

    SMO

    背景

    Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed:19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation (By similarity).

    Gene: SMO

    分子量

    86 kDa

    基因ID

    6608

    UniProt

    Q99835

    途径

    Hedgehog Signaling
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