RGS14 抗体 (Internal Region)
Quick Overview for RGS14 抗体 (Internal Region) (ABIN6258314)
抗原
See all RGS14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RGS14 Antibody detects endogenous levels of total RGS14.
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预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RGS14, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 1-566) antibody
RGS14 适用: 人 ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (C-Term) antibodyRGS14 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 230-510) antibodyRGS14 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 230-510) antibodyRGS14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (C-Term) antibodyVerified RGS14 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 1-566) antibodyRGS14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 201-250) antibodyRGS14 适用: 人, 小鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (C-Term) antibodyRGS14 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 504-516) antibodyRGS14 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
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别名
- RGS14
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背景
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Description: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation, a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)-mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal-based learning and memory.
Gene: RGS14
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分子量
- 65 kDa
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基因ID
- 10636
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UniProt
- O43566
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
抗原
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