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EZH1 抗体 (Internal Region)

This anti-EZH1 antibody is a 兔 多克隆 antibody detecting EZH1 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6258153
发货至: 中国

Quick Overview for EZH1 抗体 (Internal Region) (ABIN6258153)

抗原

See all EZH1 抗体
EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

适用

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人, 小鼠

宿主

  • 68
  • 4
  • 1

克隆类型

  • 69
  • 4
多克隆

标记

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This EZH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
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    Internal Region

    特异性

    EZH1 Antibody detects endogenous levels of total EZH1.

    预测反应

    Pig,Bovine,Horse,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human EZH1, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

    别名

    EZH1

    背景

    Description: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

    Gene: EZH1

    分子量

    85 kDa

    基因ID

    2145

    UniProt

    Q92800
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