EHMT1 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for EHMT1 抗体 (Internal Region) (ABIN6258149)
抗原
See all EHMT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- EHMT1 Antibody detects endogenous levels of total EHMT1.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human EHMT1, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (AA 1-100) antibody
EHMT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) antibodyEHMT1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) antibodyEHMT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) antibodyEHMT1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1B7B4 unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (AA 1-260) antibodyEHMT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (AA 1-100) antibodyEHMT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
有效期
- 12 months
-
-
- EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))
-
别名
- EHMT1
-
背景
-
Description: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53.
Gene: EHMT1
-
分子量
- 170 kDa
-
基因ID
- 79813
-
UniProt
- Q9H9B1
抗原
-
