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DLX5 抗体 (Internal Region)

This anti-DLX5 antibody is a 兔 多克隆 antibody detecting DLX5 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6258115
发货至: 中国

Quick Overview for DLX5 抗体 (Internal Region) (ABIN6258115)

抗原

See all DLX5 抗体
DLX5 (Distal-Less Homeobox 5 (DLX5))

适用

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人, 小鼠, 大鼠

宿主

  • 42
  • 7
  • 1
  • 1

克隆类型

  • 42
  • 9
多克隆

标记

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  • 1
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This DLX5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 8
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    Internal Region

    特异性

    DLX5 Antibody detects endogenous levels of total DLX5.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human DLX5, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • Miwa, Ito, Ohta: "Tsukushi is essential for the formation of the posterior semicircular canal that detects gait performance." in: Journal of cell communication and signaling, (2021) (PubMed).

  • 抗原

    DLX5 (Distal-Less Homeobox 5 (DLX5))

    别名

    DLX5

    背景

    Description: Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.

    Gene: DLX5

    分子量

    32 kDa

    基因ID

    1749

    UniProt

    P56178
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