DLX5 抗体 (Internal Region)
Quick Overview for DLX5 抗体 (Internal Region) (ABIN6258115)
抗原
See all DLX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- DLX5 Antibody detects endogenous levels of total DLX5.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human DLX5, corresponding to a region within the internal amino acids.
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亚型
- IgG
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应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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Tsukushi is essential for the formation of the posterior semicircular canal that detects gait performance." in: Journal of cell communication and signaling, (2021) (PubMed).
: "
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Tsukushi is essential for the formation of the posterior semicircular canal that detects gait performance." in: Journal of cell communication and signaling, (2021) (PubMed).
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- DLX5 (Distal-Less Homeobox 5 (DLX5))
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别名
- DLX5
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背景
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Description: Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.
Gene: DLX5
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分子量
- 32 kDa
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基因ID
- 1749
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UniProt
- P56178
抗原
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