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PPIF 抗体 (Internal Region)

PPIF 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258097
发货至: 中国
  • 抗原 See all PPIF 抗体
    PPIF (Peptidylprolyl Isomerase F (PPIF))
    抗原表位
    • 15
    • 9
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 70
    • 47
    • 26
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 72
    • 5
    克隆类型
    • 64
    • 13
    多克隆
    标记
    • 34
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPIF antibody is un-conjugated
    应用范围
    • 42
    • 24
    • 14
    • 13
    • 13
    • 12
    • 9
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    PPIF Antibody detects endogenous levels of total PPIF.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PPIF, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PPIF Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PPIF (Peptidylprolyl Isomerase F (PPIF))
    别名
    PPIF (PPIF 产品)
    别名
    CYP3 antibody, CyP-M antibody, Cyp-D antibody, CypD antibody, CyP-D antibody, ppif antibody, wu:fd61c06 antibody, zgc:101753 antibody, AW457192 antibody, CyP-F antibody, PPIase antibody, Cyp-40 antibody, cypf antibody, peptidylprolyl isomerase F antibody, peptidylprolyl isomerase Fa antibody, peptidylprolyl isomerase F (cyclophilin F) antibody, peptidylprolyl isomerase D antibody, peptidylprolyl isomerase F L homeolog antibody, PPIF antibody, ppifa antibody, Ppif antibody, Ppid antibody, ppif antibody, ppif.L antibody
    背景

    Description: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis, the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F1F0 ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.

    Gene: PPIF

    分子量
    22 kDa
    基因ID
    10105
    UniProt
    P30405
    途径
    Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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