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PPIF 抗体 (C-Term)

PPIF 适用: 人 WB 宿主: 兔 Polyclonal RB49693 unconjugated
产品编号 ABIN6243145
发货至: 中国
  • 抗原 See all PPIF 抗体
    PPIF (Peptidylprolyl Isomerase F (PPIF))
    抗原表位
    • 15
    • 10
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-217, C-Term
    适用
    • 70
    • 48
    • 27
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 72
    • 5
    克隆类型
    • 64
    • 13
    多克隆
    标记
    • 34
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPIF antibody is un-conjugated
    应用范围
    • 42
    • 25
    • 15
    • 13
    • 13
    • 13
    • 10
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PPIF antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-217 amino acids from the C-terminal region of human PPIF.
    克隆位点
    RB49693
    亚型
    Ig Fraction
    Top Product
    Discover our top product PPIF Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    PPIF (Peptidylprolyl Isomerase F (PPIF))
    别名
    PPIF (PPIF 产品)
    别名
    CYP3 antibody, CyP-M antibody, Cyp-D antibody, CypD antibody, CyP-D antibody, ppif antibody, wu:fd61c06 antibody, zgc:101753 antibody, AW457192 antibody, CyP-F antibody, PPIase antibody, Cyp-40 antibody, cypf antibody, peptidylprolyl isomerase F antibody, peptidylprolyl isomerase Fa antibody, peptidylprolyl isomerase F (cyclophilin F) antibody, peptidylprolyl isomerase D antibody, peptidylprolyl isomerase F L homeolog antibody, PPIF antibody, ppifa antibody, Ppif antibody, Ppid antibody, ppif antibody, ppif.L antibody
    背景
    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probablity of the mPTP leading to apoptosis or necrosis, the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress- induced necrosis. Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.
    分子量
    22040
    UniProt
    P30405
    途径
    Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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