PPIF 抗体 (Internal Region)
Quick Overview for PPIF 抗体 (Internal Region) (ABIN6258097)
抗原
See all PPIF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- PPIF Antibody detects endogenous levels of total PPIF.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PPIF, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Peptidylprolyl Isomerase F (PPIF) (AA 44-192) antibody
PPIF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) antibodyPPIF 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) (AA 21-207) antibodyPPIF 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) (AA 30-207) antibodyPPIF 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) (AA 45-196) antibodyPPIF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) (AA 30-207) antibodyPPIF 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) (Internal Region) antibodyPPIF 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) (AA 30-207) antibodyPPIF 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal AT1F5 unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) (AA 183-217), (C-Term) antibodyPPIF 适用: 人 WB 宿主: 兔 Polyclonal RB49693 unconjugated
anti-Peptidylprolyl Isomerase F (PPIF) (AA 120-207) antibodyPPIF 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PPIF (Peptidylprolyl Isomerase F (PPIF))
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别名
- PPIF
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背景
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Description: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis, the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F1F0 ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.
Gene: PPIF
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分子量
- 22 kDa
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基因ID
- 10105
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UniProt
- P30405
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途径
- Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
抗原
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