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CD55 抗体 (Internal Region)

This anti-CD55 antibody (ABIN6258004) is a Rabbit Polyclonal antibody detecting CD55 in WB, IHC, IF, ELISA, ICC. Suitable for Human, Rat.
产品编号 ABIN6258004
发货至: 中国

Quick Overview for CD55 抗体 (Internal Region) (ABIN6258004)

抗原

See all CD55 抗体
CD55 (Complement Decay-Accelerating Factor (CD55))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD55 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

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    Internal Region

    特异性

    CD55 Antibody detects endogenous levels of total CD55.

    预测反应

    Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CD55, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CD55 (Complement Decay-Accelerating Factor (CD55))

    别名

    CD55

    背景

    Description: This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829).

    Gene: CD55

    分子量

    41 kDa

    基因ID

    1604

    UniProt

    P08174

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity
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