CD55 抗体 (Internal Region)
Quick Overview for CD55 抗体 (Internal Region) (ABIN6258004)
抗原
See all CD55 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- Internal Region
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                                            特异性
- CD55 Antibody detects endogenous levels of total CD55.
- 
                                            预测反应
- Dog
- 
                                            纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 
                                            免疫原
- A synthesized peptide derived from human CD55, corresponding to a region within the internal amino acids.
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                                            亚型
- IgG
 
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                                            应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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                                            有效期
- 12 months
 
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    - CD55 (Complement Decay-Accelerating Factor (CD55))
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                                            别名
- CD55
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                                            背景
- 
                        Description: This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829). Gene: CD55 
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                                            分子量
- 41 kDa
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                                            基因ID
- 1604
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                                            UniProt
- P08174
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                                            途径
- Complement System, Regulation of Leukocyte Mediated Immunity
 抗原
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