CCL20 抗体 (Internal Region)
Quick Overview for CCL20 抗体 (Internal Region) (ABIN6257746)
抗原
See all CCL20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- CCL20 Antibody detects endogenous levels of total CCL20.
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预测反应
- Pig,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CCL20, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (PE)
CCL20 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 PE
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibodyCCL20 适用: 人 IP, FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal UCHL1 unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 24-97) antibodyCCL20 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-96) antibodyCCL20 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal A4 unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (FITC)CCL20 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 FITC
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 31-97) antibodyCCL20 适用: 人, 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 24-95) antibodyCCL20 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (APC)CCL20 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 APC
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 24-95) antibodyCCL20 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
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别名
- CCL20
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背景
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Description: Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:11352563, PubMed:11035086, PubMed:20068036). The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and various autoimmune diseases (PubMed:21376174). CCL20 acts as a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes (PubMed:9038201, PubMed:11352563). Involved in the recruitment of both the proinflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation. Required for optimal migration of thymic natural regulatory T cells (nTregs) and DN1 early thymocyte progenitor cells (By similarity). C-terminal processed forms have been shown to be equally chemotactically active for leukocytes (PubMed:11035086). Positively regulates sperm motility and chemotaxis via its binding to CCR6 which triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:23765988, PubMed:25122636). Inhibits proliferation of myeloid progenitors in colony formation assays (PubMed:9129037). May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells (By similarity). Possesses antibacterial activity towards E.coli ATCC 25922 and S.aureus ATCC 29213 (PubMed:12149255).
Gene: CCL20
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分子量
- 11 kDa
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基因ID
- 6364
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UniProt
- P78556
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途径
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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