PLCE1 抗体
Quick Overview for PLCE1 抗体 (ABIN6257434)
抗原
See all PLCE1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- PLCE1 antibody detects endogenous levels of total PLCE1
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交叉反应
- 人, 小鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
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别名
- PLCE1
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背景
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Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.
Gene: PLCE1
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基因ID
- 51196
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UniProt
- Q9P212
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途径
- EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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