PPP4R2 抗体 (Internal Region)
Quick Overview for PPP4R2 抗体 (Internal Region) (ABIN6257426)
抗原
See all PPP4R2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- PPP4R2 Antibody detects endogenous levels of total PPP4R2.
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预测反应
- Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PPP4R2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) antibody
PPP4R2 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-360) antibodyPPP4R2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 288-337) antibodyPPP4R2 适用: 人, 小鼠, 猴, 大鼠, Cow, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (C-Term) antibodyPPP4R2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (C-Term) antibodyPPP4R2 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
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别名
- PPP4R2
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背景
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Description: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair.
Gene: PPP4R2
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分子量
- 50 kDa
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基因ID
- 151987
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UniProt
- Q9NY27
抗原
-
