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ZBTB33 抗体 (N-Term)

The 兔 多克隆 anti-ZBTB33 antibody is suitable to detect ZBTB33 in samples from 人 和 小鼠. It has been validated for WB, ELISA, IF 和 ICC.
产品编号 ABIN6257304
发货至: 中国
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Quick Overview for ZBTB33 抗体 (N-Term) (ABIN6257304)

抗原

See all ZBTB33 抗体
ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

适用

  • 27
  • 11
  • 8
  • 8
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 24
  • 4

克隆类型

  • 20
  • 8
多克隆

标记

  • 24
  • 2
  • 1
  • 1
This ZBTB33 antibody is un-conjugated

应用范围

  • 20
  • 12
  • 7
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    特异性

    ZBTB33 Antibody detects endogenous levels of total ZBTB33.

    预测反应

    Bovine,Horse,Sheep

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ZBTB33, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

    别名

    ZBTB33

    背景

    Description: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453).

    Gene: ZBTB33

    分子量

    95 kDa

    基因ID

    10009

    UniProt

    Q86T24
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