ING4 抗体 (Internal Region)
Quick Overview for ING4 抗体 (Internal Region) (ABIN6257280)
抗原
See all ING4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ING4 Antibody detects endogenous levels of total ING4.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ING4, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibody
ING4 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibodyING4 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibodyING4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8F7 unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 110-159) antibodyING4 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-190) antibodyING4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 162-195), (C-Term) antibodyING4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB47839 unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 75-249) antibodyING4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (Internal Region) antibodyING4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 150-175) antibodyING4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
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别名
- ING4
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背景
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Description: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).
Gene: ING4
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分子量
- 29 kDa
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基因ID
- 51147
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UniProt
- Q9UNL4
抗原
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