MYST2 抗体 (Internal Region)
Quick Overview for MYST2 抗体 (Internal Region) (ABIN6257254)
抗原
See all MYST2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- MYST2 Antibody detects endogenous levels of total MYST2.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MYST2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 47, Issue 5, pp. 2159-2169, (2018) (PubMed).
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: "Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 47, Issue 5, pp. 2159-2169, (2018) (PubMed).
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- MYST2 (MYST Histone Acetyltransferase 2 (MYST2))
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别名
- KAT7
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背景
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Description: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Involved in H3K14 (histone H3 lysine 14) acetylation and cell proliferation (By similarity). Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1 (PubMed:18832067). Specifically represses AR-mediated transcription.
Gene: KAT7
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分子量
- 75 kDa
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基因ID
- 11143
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UniProt
- O95251
抗原
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