EIF3E 抗体 (C-Term)
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Quick Overview for EIF3E 抗体 (C-Term) (ABIN6257160)
抗原
See all EIF3E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- INT6 Antibody
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特异性
- INT6 Antibody detects endogenous levels of total INT6.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human INT6, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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别名
- INT6
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背景
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Description: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).
Gene: INTS6
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分子量
- 117 kDa
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基因ID
- 26512
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UniProt
- Q9UL03
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途径
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
抗原
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