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BMP10 抗体 (Internal Region)

The 兔 多克隆 anti-BMP10 antibody (ABIN6256960) specifically detects BMP10 in WB, ELISA, ICC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN6256960
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BMP10 抗体 (Internal Region) (ABIN6256960)

抗原

See all BMP10 抗体
BMP10 (Bone Morphogenetic Protein 10 (BMP10))

适用

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宿主

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克隆类型

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多克隆

标记

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This BMP10 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
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    Internal Region

    特异性

    BMP10 Antibody detects endogenous levels of total BMP10.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human BMP10, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    BMP10 (Bone Morphogenetic Protein 10 (BMP10))

    别名

    BMP10

    背景

    Description: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

    Gene: BMP10

    分子量

    48 kDa

    基因ID

    27302

    UniProt

    O95393

    途径

    Hormone Activity, Regulation of Muscle Cell Differentiation
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