CD166 抗体 (N-Term)
Quick Overview for CD166 抗体 (N-Term) (ABIN6256927)
抗原
See all CD166 (ALCAM) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- CD166 Antibody detects endogenous levels of total CD166.
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预测反应
- Pig,Bovine,Horse,Sheep
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CD166, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 48-216) antibody
ALCAM 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4H9A5 unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 48-216) antibodyALCAM 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8E12C7 unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 227-381) antibodyALCAM 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2F1B12 unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 405-524) antibodyALCAM 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 48-216) antibodyALCAM 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 58-87) antibodyALCAM 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-527) antibodyALCAM 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-527) antibodyALCAM 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 5-2# unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-527) antibodyALCAM 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 167-406) antibodyALCAM 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
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别名
- ALCAM
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背景
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Description: Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts (PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed:15048703, PubMed:16352806, PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed:15294938, PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed:15496415, PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed:15496415, PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis, required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance, axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).
Gene: ALCAM
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分子量
- 100-105 kDa
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基因ID
- 214
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UniProt
- Q13740
抗原
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