KDM5D 抗体 (C-Term)
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Quick Overview for KDM5D 抗体 (C-Term) (ABIN6256832)
抗原
See all KDM5D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- JAD1D Antibody detects endogenous levels of total JAD1D.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human JAD1D, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 5D (KDM5D) (AA 127-230) antibody
KDM5D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C6 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- KDM5D (Lysine (K)-Specific Demethylase 5D (KDM5D))
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别名
- KDM5D
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背景
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Description: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes, in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks.
Gene: KDM5D
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基因ID
- 8284
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UniProt
- Q9BY66
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途径
- Warburg Effect
抗原
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