CAMKII gamma 抗体 (pTyr231)
Our Local Distributor
北京 101111
Quick Overview for CAMKII gamma 抗体 (pTyr231) (ABIN6256678)
抗原
See all CAMKII gamma (CAMK2G) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr231
-
特异性
- Phospho-CaMKII (Tyr231) Antibody detects endogenous levels of CaMKII.
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
免疫原
- A synthesized peptide derived from human CaMKII around the phosphorylation site of Tyr231.
-
亚型
- IgG
-
-
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) (AA 309-338), (C-Term) antibody
CAMK2G 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1246 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) (AA 322-481) antibodyCAMK2G 适用: 人, 大鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8G10C1 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibodyCAMK2G 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC, RIA 宿主: 小鼠 Monoclonal 6G9 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibodyCAMK2G 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 小鼠 Monoclonal 22B1 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (Atto 390)CAMK2G 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC, RIA 宿主: 小鼠 Monoclonal 6G9 Atto 390
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (Atto 488)CAMK2G 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC, RIA 宿主: 小鼠 Monoclonal 6G9 Atto 488
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (Atto 594)CAMK2G 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC, RIA 宿主: 小鼠 Monoclonal 6G9 Atto 594
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (Biotin)CAMK2G 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC, RIA 宿主: 小鼠 Monoclonal 6G9 Biotin
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (FITC)CAMK2G 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC, RIA 宿主: 小鼠 Monoclonal 6G9 FITC
anti-Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) antibody (APC)CAMK2G 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC, RIA 宿主: 小鼠 Monoclonal 6G9 APC
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
-
有效期
- 12 months
-
-
- CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))
-
别名
- CaMKII
-
背景
-
Description: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.
Gene: CAMK2B
-
分子量
- 50kDa
-
基因ID
- 816
-
UniProt
- Q13554
-
途径
- WNT signaling, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-
