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NOS2 抗体 (pTyr151)

NOS2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256645
发货至: 中国
  • 抗原 See all NOS2 抗体
    NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
    抗原表位
    • 16
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    • 1
    • 1
    • 1
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    pTyr151
    适用
    • 105
    • 67
    • 66
    • 17
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 123
    • 9
    克隆类型
    • 118
    • 14
    多克隆
    标记
    • 64
    • 16
    • 8
    • 6
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    • 3
    • 3
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    • 2
    This NOS2 antibody is un-conjugated
    应用范围
    • 105
    • 41
    • 32
    • 31
    • 27
    • 26
    • 20
    • 17
    • 16
    • 13
    • 7
    • 4
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    Phospho-iNOS (Tyr151) Antibody detects endogenous levels of iNOS only when phosphorylated at Tyrosine 151.
    预测反应
    Bovine,Horse,Sheep,Dog
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human iNOS around the phosphorylation site of Tyr151.
    亚型
    IgG
    Top Product
    Discover our top product NOS2 Primary Antibody
  • 应用备注
    IHC 1:50-1:200, WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
    别名
    NOS2 (NOS2 产品)
    别名
    HEP-NOS antibody, INOS antibody, NOS antibody, NOS2A antibody, NOS-II antibody, Nos-2 antibody, Nos2a antibody, i-NOS antibody, iNOS antibody, iNos antibody, NOS2a antibody, NOS2 antibody, BmNOS2 antibody, Nsl antibody, nos2 antibody, nitric oxide synthase 2 antibody, nitric oxide synthase 2, inducible antibody, inducible nitric oxide synthase antibody, inducible nitric-oxide synthase antibody, nanos C2HC-type zinc finger 2 antibody, NOS2 antibody, Nos2 antibody, nos2 antibody, LOC396821 antibody, NANOS2 antibody
    背景

    Description: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109).

    Gene: NOS2

    分子量
    kDa
    基因ID
    4843
    UniProt
    P35228
    途径
    Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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