PRKACB 抗体 (pThr197)
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北京 101111
Quick Overview for PRKACB 抗体 (pThr197) (ABIN6256496)
抗原
See all PRKACB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr197
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特异性
- Phospho-PKA beta (Thr197) Antibody detects endogenous levels of PKA beta only when phosphorylated at Thr198, which site historically referenced as Thr197.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human PKA beta around the phosphorylation site of Thr197.
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亚型
- IgG
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anti-Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB) (AA 1-351) antibody
PRKACB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB) (AA 2-53), (Catalytic Subunit) antibodyPRKACB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB) (AA 14-43), (N-Term) antibodyPRKACB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3546 unconjugated
anti-Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB) antibodyPRKACB 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB) (C-Term) antibodyPRKACB 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB) (AA 1-257) antibodyPRKACB 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2G8-1D12 unconjugated
anti-Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB) (C-Term) antibodyPRKACB 适用: 人, 大鼠, 小鼠, Cow, Pig, 豚鼠, 马, 兔, 犬, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB) (N-Term) antibodyPRKACB 适用: 人, 大鼠, 小鼠, Cow, Pig, 豚鼠, 马, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))
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别名
- PRKACB
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背景
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Description: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (PubMed:12420224, PubMed:21423175). Phosphorylates GPKOW which regulates its ability to bind RNA (PubMed:21880142).
Gene: PRKACB
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分子量
- 40 kDa
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基因ID
- 5567
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UniProt
- P22694
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途径
- AMPK Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism
抗原
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