GRIN1/NMDAR1 抗体 (pSer890)
Quick Overview for GRIN1/NMDAR1 抗体 (pSer890) (ABIN6256445)
抗原
See all GRIN1/NMDAR1 (GRIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- pSer890
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                                            特异性
- Phospho-NMDAR1 (Ser890) Antibody detects endogenous levels of NMDAR1 only when phosphorylated at Serine 890.
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                                            预测反应
- Pig,Bovine,Horse,Dog,Chicken,Xenopus
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                                            纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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                                            免疫原
- A synthesized peptide derived from human NMDAR1 around the phosphorylation site of Ser890.
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                                            亚型
- IgG
 
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                                            应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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                                            有效期
- 12 months
 
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    - GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
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                                            别名
- GRIN1
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                                            背景
- 
                        Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761). Gene: GRIN1 
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                                            分子量
- 105kDa
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                                            基因ID
- 2902
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                                            UniProt
- Q05586
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                                            途径
- Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
 抗原
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