FOXO3 抗体 (pSer413)
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北京 101111
Quick Overview for FOXO3 抗体 (pSer413) (ABIN6256325)
抗原
See all FOXO3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer413
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特异性
- Phospho-FoxO3a (Ser413) Antibody detects endogenous levels of FoxO3a.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human FoxO3a around the phosphorylation site of Ser413.
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亚型
- IgG
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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 适用: 人 WB, IF, ICC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 471-673) antibodyFOXO3 适用: 人, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) antibodyFOXO3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1E2 unconjugated Recombinant Antibody
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- FOXO3 (Forkhead Box O3 (FOXO3))
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别名
- FoxO3a
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背景
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Description: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress (PubMed:10102273, PubMed:16751106). Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (PubMed:21329882). Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (PubMed:21329882). In response to metabolic stress, translocates into the mitochondria where it promotes mtDNA transcription (PubMed:23283301).
Gene: FOXO3
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分子量
- 82-97kDa
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基因ID
- 2309
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UniProt
- O43524
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
抗原
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