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c-FOS 抗体 (pSer32)

This 兔 多克隆 antibody specifically detects c-FOS in WB 和 IHC. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN6256268
发货至: 中国
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Quick Overview for c-FOS 抗体 (pSer32) (ABIN6256268)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This c-FOS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    pSer32

    特异性

    Phospho-FOS (Ser32) Antibody detects endogenous levels of FOS.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human FOS around the phosphorylation site of Ser32.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    FOS

    背景

    Description: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    Gene: FOS

    分子量

    62kDa

    基因ID

    2353

    UniProt

    P01100

    途径

    S100 Proteins
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