GATA4 抗体 (pSer262)
Quick Overview for GATA4 抗体 (pSer262) (ABIN6256227)
抗原
See all GATA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer262
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特异性
- Phospho-GATA4 (Ser262) Antibody detects endogenous levels of GATA4 only when phosphorylated at Serine 262.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human GATA4 around the phosphorylation site of Ser262.
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亚型
- IgG
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anti-GATA Binding Protein 4 (GATA4) (pSer105) antibody
GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) antibodyGATA4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 228-440) antibodyGATA4 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 50-150) antibodyGATA4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 261-360) antibodyGATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 201-442) antibodyGATA4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 330-380) antibodyGATA4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 343-442) antibodyGATA4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C6 unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 296-442) antibodyGATA4 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1H8 unconjugated
anti-GATA Binding Protein 4 (GATA4) antibodyGATA4 适用: 人, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal 6H10 unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- GATA4 (GATA Binding Protein 4 (GATA4))
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别名
- GATA4
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背景
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Description: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735).
Gene: GATA4
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分子量
- 48kDa
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基因ID
- 2626
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UniProt
- P43694
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途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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