Tuberin 抗体 (pSer1387)
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Quick Overview for Tuberin 抗体 (pSer1387) (ABIN6256137)
抗原
See all Tuberin (TSC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1387
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特异性
- Phospho-Tuberin/TSC2 (Ser1387) Antibody detects endogenous levels of Tuberin/TSC2.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Ser1387.
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亚型
- IgG
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anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibody
TSC2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB13393 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1611-1807) antibodyTSC2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibodyTSC2 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) antibodyKD Validated TSC2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1120 unconjugated Recombinant Antibody
anti-Tuberous Sclerosis 2 (TSC2) antibodyKD Validated TSC2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1000 unconjugated Recombinant Antibody
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 900-1150) antibodyTSC2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1397-1426) antibodyTSC2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB42388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pSer1387) antibodyTSC2 适用: 人 DB, IF 宿主: 兔 Polyclonal RB11388 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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别名
- Tuberin/TSC2
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背景
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Description: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, PubMed:28215400). Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1 (PubMed:15340059). May also play a role in microtubule-mediated protein transport (By similarity). Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 (By similarity).
Gene: TSC2
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分子量
- 200kDa
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基因ID
- 7249
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UniProt
- P49815
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途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
抗原
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