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ESR2 抗体 (pSer105)

This anti-ESR2 antibody is a 兔 多克隆 antibody detecting ESR2 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6256093
发货至: 中国

Quick Overview for ESR2 抗体 (pSer105) (ABIN6256093)

抗原

See all ESR2 抗体
ESR2 (Estrogen Receptor 2 (ESR2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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  • 50
多克隆

标记

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This ESR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    pSer105

    特异性

    Phospho-Estrogen Receptor-beta (Ser105) Antibody detects endogenous levels of Estrogen Receptor-beta only when phosphorylated at Serine 105.

    预测反应

    Horse,Sheep,Dog,Chicken

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Estrogen Receptor- beta around the phosphorylation site of Ser105.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ESR2 (Estrogen Receptor 2 (ESR2))

    别名

    ESR2

    背景

    Description: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

    Gene: ESR2

    分子量

    59kDa

    基因ID

    2100

    UniProt

    Q92731

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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