BMX 抗体 (pTyr566)
Quick Overview for BMX 抗体 (pTyr566) (ABIN6255953)
抗原
See all BMX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr566
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特异性
- Phospho-BMX (Tyr566) Antibody detects endogenous levels of BMX only when phosphorylated at Tyrosine 566.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human BMX around the phosphorylation site of Tyr566.
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亚型
- IgG
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anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 287-523) antibody
BMX 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (C-Term) antibodyBMX 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (N-Term) antibodyBMX 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 65-280) antibodyBMX 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 150-280) antibodyBMX 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (pTyr566) antibodyBMX 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 65-280) antibodyBMX 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 209-446) antibodyBMX 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) antibodyBMX 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 532-581) antibodyBMX 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
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别名
- BMX
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背景
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Description: Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3, a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a role in programming adaptive cytoprotection against extracellular stress in different cell systems, salivary epithelial cells, brain endothelial cells, and dermal fibroblasts. May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1. May also play a role in the growth and differentiation of hematopoietic cells, as well as in signal transduction in endocardial and arterial endothelial cells.
Gene: BMX
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分子量
- 78kDa
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基因ID
- 660
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UniProt
- P51813
抗原
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