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- 抗原 See all BMX 抗体
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BMX antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from N-terminal of Human BMX.
- 亚型
- IgG
- Top Product
- Discover our top product BMX Primary Antibody
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anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 287-523) antibody
BMX 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (C-Term) antibodyBMX 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 65-280) antibodyBMX 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 150-280) antibodyBMX 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (pTyr566) antibodyBMX 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (pTyr566) antibodyBMX 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 65-280) antibodyBMX 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) (AA 209-446) antibodyBMX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) antibodyBMX 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BMX Non-Receptor Tyrosine Kinase (BMX) antibodyBMX 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C6 unconjugated
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- 应用备注
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
- 别名
- BMX (BMX 产品)
- 别名
- BMX antibody, ETK antibody, PSCTK2 antibody, PSCTK3 antibody, Etk antibody, Etk/Bmx antibody, Tyro8 antibody, RGD1565643 antibody, BMX non-receptor tyrosine kinase antibody, BMX antibody, bmx antibody, Bmx antibody
- 背景
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Background: Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3, a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a role in programming adaptive cytoprotection against extracellular stress in different cell systems, salivary epithelial cells, brain endothelial cells, and dermal fibroblasts. May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1. May also play a role in the growth and differentiation of hematopoietic cells, as well as in signal transduction in endocardial and arterial endothelial cells.
Tamagnone L., Oncogene 9:3683-3688(1994).
Qiu Y., Proc. Natl. Acad. Sci. U.S.A. 95:3644-3649(1998).
Fuortes M., Thesis (1994), Cornell University, United States.Aliases: Bmx antibody, BMX non receptor tyrosine kinase antibody, BMX_HUMAN antibody, BONE MARROW KINASE, X-LINKED antibody, Bone marrow tyrosine kinase gene in chromosome X protein antibody, Cytoplasmic tyrosine protein kinase BMX antibody, Cytoplasmic tyrosine-protein kinase BMX antibody, Epithelial and endothelial tyrosine kinase antibody, ETK antibody, NKT38 antibody, NTK 38 antibody, NTK38 antibody, Protein tyrosine kinase BMX antibody, PSCTK 2 antibody, PSCTK 3 antibody, PSCTK2 antibody, PSCTK3 antibody
- UniProt
- P51813
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