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JAK1 抗体 (pTyr1022, pTyr1023)

Name: JAK1 抗体 (pTyr1022, pTyr1023)
SKU: ABIN6255762
Availability: OutOfStock

This anti-JAK1 antibody is a 兔多克隆 antibody detecting JAK1 in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 4+ publications.

Western blot analysis of JAK1 phosphorylation expression in A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (JAK1 抗体 (pTyr1022, pTyr1023))

ABIN6267072 at 1/100 staining mouse lung tissue sections by IHC-P. (JAK1 抗体 (pTyr1022, pTyr1023))

IHC

ABIN6267072 at 1/100 staining mouse testis tissue sections by IHC-P. (JAK1 抗体 (pTyr1022, pTyr1023))

IHC

ABIN6267072 at 1/100 staining rat appendiceal tissue sections by IHC-P. (JAK1 抗体 (pTyr1022, pTyr1023))

12 images

(4 references)

产品编号 ABIN6255762

发货至: 中国

Quick Overview for JAK1 抗体 (pTyr1022, pTyr1023) (ABIN6255762)

抗原

See all JAK1 抗体

JAK1 (Janus Kinase 1 (JAK1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This JAK1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

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pTyr1022, pTyr1023

特异性

Phospho-JAK1 (Tyr1022/Tyr1023) Antibody detects endogenous levels of JAK1 only when phosphorylated at Tyr1034/Tyr1035, which site historically referenced as Tyr1022/Tyr1023.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

免疫原

A synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022/Tyr1023.

亚型

IgG
anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (AA 960-1040) antibody
JAK1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated

anti-Janus Kinase 1 (JAK1) (AA 1020-1024) antibody
JAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) antibody
JAK1 适用: 人, 大鼠 WB, IP 宿主: 小鼠 Monoclonal 7B1-B6-G7 unconjugated

anti-Janus Kinase 1 (JAK1) (AA 172-204), (N-Term) antibody
JAK1 适用: 人 WB 宿主: 兔 Polyclonal RB43809 unconjugated

anti-Janus Kinase 1 (JAK1) (AA 866-899), (C-Term) antibody
JAK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB43812 unconjugated

anti-Janus Kinase 1 (JAK1) (Ser639) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (C-Term) antibody
JAK1 适用: 人, 小鼠, 大鼠, 小鸡, 犬, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (pTyr1034), (pTyr1035) antibody
JAK1 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (AA 596-841) antibody
JAK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:500, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Fukasawa, Yoshizaki, Ebata, Yoshizaki-Ogawa, Asano, Enomoto, Miyagawa, Kazoe, Mawatari, Kitamori, Sato: "Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model." in: eLife, Vol. 10, (2021) (PubMed).

Chen, Zhou, Liu, Huang, Liu, Kang, Chen, Guo, Zhu, Sun: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).

Tu, Yu, Zhang, Shi, Xu, Hu, Gan, He, Dong, Han, Huang, Pan, Zhang: "A novel fluorinated triazole derivative suppresses macrophage activation and alleviates experimental colitis via a Twist1-dependent pathway." in: Biochemical pharmacology, Vol. 155, pp. 275-287, (2018) (PubMed).

Bai, Wang, Han, Xie, Ji, Yin, Chen, Wang, Jiang, Qi, Jiang: "BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo." in: Molecular carcinogenesis, Vol. 56, Issue 3, pp. 1137-1149, (2017) (PubMed).
抗原

JAK1 (Janus Kinase 1 (JAK1))

别名

JAK1

背景

Description: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).
Gene: JAK1

分子量

130kDa

基因ID

3716

UniProt

P23458

途径

JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response