HDAC5 抗体 (pSer498)
(1 reference)Quick Overview for HDAC5 抗体 (pSer498) (ABIN6255378)
抗原
See all HDAC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer498
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特异性
- Phospho-HDAC5 (Ser498) Antibody detects endogenous levels of HDAC5 only when phosphorylated at Serine 498.
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预测反应
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498.
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亚型
- IgG
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anti-Histone Deacetylase 5 (HDAC5) (C-Term) antibody
HDAC5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (AA 550-650) antibodyHDAC5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) antibodyHDAC5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (AA 330-429) antibodyHDAC5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G2 unconjugated
anti-Histone Deacetylase 5 (HDAC5) antibodyHDAC5 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (pSer259) antibodyHDAC5 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (C-Term) antibodyHDAC5 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (AA 1-100) antibodyHDAC5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (C-Term) antibodyHDAC5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (Tyr512) antibodyHDAC5 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation." in: Cellular and molecular gastroenterology and hepatology, Vol. 12, Issue 4, pp. 1457-1477, (2022) (PubMed).
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: "Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation." in: Cellular and molecular gastroenterology and hepatology, Vol. 12, Issue 4, pp. 1457-1477, (2022) (PubMed).
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- HDAC5 (Histone Deacetylase 5 (HDAC5))
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别名
- HDAC5
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背景
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Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Gene: HDAC5
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分子量
- 124kDa
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基因ID
- 10014
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UniProt
- Q9UQL6
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
抗原
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