SREBF1 抗体 (pSer439)
Quick Overview for SREBF1 抗体 (pSer439) (ABIN6255339)
抗原
See all SREBF1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer439
-
特异性
- Phospho-SREBP1 (Ser439) Antibody detects endogenous levels of SREBP1 only when phosphorylated at Serine 439.
-
预测反应
- Pig,Horse,Sheep,Dog
-
纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
免疫原
- A synthesized peptide derived from human SREBP1 around the phosphorylation site of Ser439.
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
-
别名
- SREBF1
-
背景
-
Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Gene: SREBF1
-
分子量
- 122kDa
-
基因ID
- 6720
-
UniProt
- P36956
-
途径
- AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
抗原
-