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HDAC8 抗体 (pSer39)

This anti-HDAC8 antibody is a 兔 多克隆 antibody detecting HDAC8 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6255291
发货至: 中国

Quick Overview for HDAC8 抗体 (pSer39) (ABIN6255291)

抗原

See all HDAC8 抗体
HDAC8 (Histone Deacetylase 8 (HDAC8))

适用

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人, 小鼠, 大鼠

宿主

  • 95
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克隆类型

  • 85
  • 16
多克隆

标记

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This HDAC8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    pSer39

    特异性

    Phospho-HDAC8 (Ser39) Antibody detects endogenous levels of HDAC8 only when phosphorylated at Serine 39.

    预测反应

    Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    HDAC8 (Histone Deacetylase 8 (HDAC8))

    别名

    HDAC8

    背景

    Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

    Gene: HDAC8

    分子量

    42kDa

    基因ID

    55869

    UniProt

    Q9BY41

    途径

    Cellular Glucan Metabolic Process
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