ATG13 抗体 (pSer355)
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北京 101111
Quick Overview for ATG13 抗体 (pSer355) (ABIN6255252)
抗原
See all ATG13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer355
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特异性
- Phospho-Atg13 (Ser355) Antibody detects endogenous levels of Atg13.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human Atg13 around the phosphorylation site of Ser355.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- ATG13 (Autophagy Related 13 (ATG13))
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别名
- Atg13
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背景
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Description: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Gene: ATG13
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分子量
- 72kDa
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基因ID
- 9776
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UniProt
- O75143
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途径
- PI3K-Akt Signaling, Autophagy
抗原
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