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TCP1 alpha/CCTA 抗体 (pSer160, pSer162)

The 兔 多克隆 anti-TCP1 alpha/CCTA antibody (ABIN6255010) specifically detects TCP1 alpha/CCTA in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6255010
发货至: 中国
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Quick Overview for TCP1 alpha/CCTA 抗体 (pSer160, pSer162) (ABIN6255010)

抗原

See all TCP1 alpha/CCTA (TCP1) 抗体
TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

适用

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人, 小鼠, 大鼠

宿主

  • 191
  • 60
  • 26
  • 1
  • 1

克隆类型

  • 143
  • 136
多克隆

标记

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This TCP1 alpha/CCTA antibody is un-conjugated

应用范围

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  • 35
  • 12
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 40
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    pSer160, pSer162

    特异性

    Phospho-p63 (Ser160/162) Antibody detects endogenous levels of p63.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human p63 around the phosphorylation site of Ser160/162.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

    别名

    p63

    背景

    Description: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.

    Gene: TP63

    分子量

    75kDa

    基因ID

    8626

    UniProt

    Q9H3D4
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