ErbB2/Her2 抗体 (C-Term)
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Quick Overview for ErbB2/Her2 抗体 (C-Term) (ABIN6254225)
抗原
See all ErbB2/Her2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-ERBB2
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序列
- MPHPPPAFSP AFDNLYYWDQ DPPERGAPPS TFKGTPTAEN PEYLGLDVPV
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特异性
- Detects endogenous levels of ERBB2 by Western blot.
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产品特性
- Erb-b2 receptor tyrosine kinase
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纯化方法
- Epitope affinity purified
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免疫原
- Purified recombinant peptide derived from within residues 1,177 aa to the C-terminus of human ERBB2 produced in E. coli.
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亚型
- IgG
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应用备注
- WB:1:500-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
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限制
- 仅限研究用
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缓冲液
- PBS, 20 % glycerol and 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody solution should be gently mixed before use.
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储存条件
- 4 °C,-20 °C
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储存方法
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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别名
- ERBB2
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背景
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Goat polyclonal antibody to ERBB2. This protein is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases containing a single transmembrane domain and has an approximate molecular weight of 185 kDa. ERBB2 contains no ligand binding domain and interacts with other EGF receptor family members to form a heterodimer, stabilize ligand binding, and enhance kinase-mediated downstream signalling. It has been shown to be involved in embryonic development and cancer progression.
CD340, erb-b2 receptor tyrosine kinase 2, HER2, HER-2, HER-2/neu, MLN 19, NEU, NGL and TKR1 antibody.
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分子量
- 185 kDa
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
抗原
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