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FMR1 抗体 (pSer499)

This anti-FMR1 antibody is a 兔 多克隆 antibody detecting FMR1 in WB. Suitable for 大鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN6254033
发货至: 中国

Quick Overview for FMR1 抗体 (pSer499) (ABIN6254033)

抗原

See all FMR1 抗体
FMR1 (Fragile X Mental Retardation 1 (FMR1))

适用

  • 78
  • 55
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  • 15
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  • 2
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大鼠

宿主

  • 62
  • 19
  • 2

克隆类型

  • 55
  • 28
多克隆

标记

  • 50
  • 4
  • 2
  • 2
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  • 2
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  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FMR1 antibody is un-conjugated

应用范围

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  • 25
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  • 15
  • 14
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  • 9
  • 5
  • 4
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  • 1
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Western Blotting (WB)
  • 抗原表位

    • 15
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    • 5
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
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    pSer499

    交叉反应

    小鼠, 大鼠

    预测反应

    bovine, canine, chicken, human, mouse, non-human primates, sheep, Xenopus, zebra fish

    纯化方法

    Antigen Affinity Purified from Pooled Serum

    免疫原

    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser499 conjugated to KLH
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    储存条件

    -20 °C
  • Bartley, OKeefe, Blice-Baum, Mihailescu, Gong, Miyares, Karaca, Bordey: "Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP." in: eNeuro, Vol. 3, Issue 6, (2017) (PubMed).

    Reynolds, Smith, Jefferson, Lugo: "Comparison of Equivalence between Two Commercially Available S499-Phosphorylated FMRP Antibodies in Mice." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143134, (2016) (PubMed).

    Guimarães-Souza, Perche, Morgans, Duvoisin, Calaza: "Fragile X Mental Retardation Protein expression in the retina is regulated by light." in: Experimental eye research, Vol. 146, pp. 72-82, (2016) (PubMed).

    Bartley, OKeefe, Bordey: "FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity." in: PLoS ONE, Vol. 9, Issue 5, pp. e96956, (2015) (PubMed).

  • 抗原

    FMR1 (Fragile X Mental Retardation 1 (FMR1))

    别名

    FMR1

    分子量

    '71 kDa

    基因ID

    24948

    UniProt

    Q80WE1

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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